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Depressive Disorder, Major MeSH Descriptor Data 2021


MeSH Heading
Depressive Disorder, Major
Tree Number(s)
F03.600.300.375
Unique ID
D003865
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003865
Scope Note
Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
Entry Version
DEPRESSIVE DIS MAJOR
Entry Term(s)
Depression, Involutional
Major Depressive Disorder
Melancholia, Involutional
Paraphrenia, Involutional
Psychosis, Involutional
Public MeSH Note
81; was PSYCHOSES, INVOLUTIONAL 1963-80
Online Note
use DEPRESSION, INVOLUTIONAL to search PSYCHOSES, INVOLUTIONAL & MELANCHOLIA, INVOLUTIONAL 1966-80
History Note
81; was PSYCHOSES, INVOLUTIONAL 1963-80; MELANCHOLIA, INVOLUTIONAL was see under PSYCHOSES, INVOLUTIONAL 1963-78
Date Established
1981/01/01
Date of Entry
1999/01/01
Revision Date
2019/03/22
Depressive Disorder, Major Preferred
Paraphrenia, Involutional Narrower
Psychosis, Involutional Related
Depression, Involutional Related
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