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Dianhydrogalactitol MeSH Descriptor Data 2023


MeSH Heading
Dianhydrogalactitol
Tree Number(s)
D02.033.800.400.350
D09.853.400.350
Unique ID
D003961
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003961
Scope Note
One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.
Entry Term(s)
1,2,5,6-Dianhydrogalactitol
1,2-5,6-Dianhydrogalactitol
Dianhydrodulcitol
Diepoxydulcitol
Diepoxygalactitol
NSC-132313
Pharm Action
Antineoplastic Agents, Alkylating
Registry Number
4S465RYF7M
Related Numbers
23261-20-3
CAS Type 1 Name
Galactitol, 1,2:5,6-dianhydro-
Previous Indexing
Alcohols (1966-1971)
Dulcitol (1972-1978)
Ethers, Cyclic (1966-1978)
Public MeSH Note
91; was see under SUGAR ALCOHOLS 1979-90
History Note
91(79); was see under SUGAR ALCOHOLS 1979-90
Date Established
1991/01/01
Date of Entry
1978/02/07
Revision Date
2018/07/02
Dianhydrogalactitol Preferred
NSC-132313 Narrower
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