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Diphenoxylate MeSH Descriptor Data 2023


MeSH Heading
Diphenoxylate
Tree Number(s)
D03.066.399.300
D03.383.621.349.300
Unique ID
D004157
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004157
Scope Note
A MEPERIDINE congener used as an antidiarrheal, usually in combination with ATROPINE. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity.
Entry Term(s)
Diphenoxylate Hydrochloride
Diphenoxylate Monohydrochloride
Pharm Action
Analgesics, Opioid
Antidiarrheals
Registry Number
73312P173G
Related Numbers
915-30-0
W24OD7YW48
CAS Type 1 Name
4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester
Previous Indexing
Isonipecotic Acids (1970-1974)
Nitriles (1974)
Public MeSH Note
91; was see under ISONIPECOTIC ACIDS 1975-90
History Note
91(75); was see under ISONIPECOTIC ACIDS 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/11
Revision Date
2016/05/31
Diphenoxylate Preferred
Diphenoxylate Hydrochloride Narrower
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