- Concept UI
- M0006600
- Registry Numbers
- TR3MLJ1UAI
- Related Numbers
- 97-77-8
- Scope Note
- A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
- Terms
-
Disulfiram
Preferred Term
Term UI
T012814
Date01/01/1999
LexicalTag
NON
ThesaurusID
-
Tetraethylthiuram Disulfide
Term UI
T012815
Date03/29/1974
LexicalTag
NON
ThesaurusID
-
Bis(diethylthiocarbamoyl) Disulfide
Term UI
T012816
Date07/31/1980
LexicalTag
NON
ThesaurusID
-
Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
Term UI
T012817
Date11/22/1993
LexicalTag
NON
ThesaurusID
NLM (1995)