NLM Logo

Dithionitrobenzoic Acid MeSH Descriptor Data 2022


MeSH Heading
Dithionitrobenzoic Acid
Tree Number(s)
D02.241.223.100.600.300
D02.455.426.559.389.127.650.300
Unique ID
D004228
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004228
Scope Note
A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.
Entry Term(s)
5,5'-Dithiobis(2-nitrobenzoic Acid)
5,5'-Dithiobis(nitrobenzoate)
DTNB
Ellman's Reagent
Pharm Action
Sulfhydryl Reagents
Registry Number
9BZQ3U62JX
Related Numbers
69-78-3
CAS Type 1 Name
Benzoic acid, 3,3'-dithiobis(6-nitro)-
Previous Indexing
Benzoates (1969-1974)
Disulfides (1972-1974)
Nitro Compounds (1972-1974)
Public MeSH Note
91; was see under NITROBENZOATES 1975-90
History Note
91(75); was see under NITROBENZOATES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/14
Revision Date
2013/07/08
Dithionitrobenzoic Acid Preferred
5,5'-Dithiobis(nitrobenzoate) Narrower
page delivered in 0.161s