MeSH Browser

MeSH Heading: Enkephalin, Methionine
Tree Number(s): D12.644.400.575.281.381; D12.776.631.650.575.281.381
Unique ID: D004744
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004744
Scope Note: One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by the amino acid METHIONINE in position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Entry Version: ENKEPHALIN MET
Entry Term(s): 5-Methionine Enkephalin; Met(5)-Enkephalin; Met-Enkephalin; Methionine Enkephalin
Pharm Action: Neurotransmitter Agents
CAS Type 1 Name: Tyr-Gly-Gly-Phe-Met
Previous Indexing: Enkephalins (Aug 1977-1982); Nerve Tissue Proteins (1966-Jul 1977); Peptides (1966-Jul 1977)
Public MeSH Note: 83
History Note: 83
Date Established: 1983/01/01
Date of Entry: 1982/05/04
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0007455
Scope Note: One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by the amino acid METHIONINE in position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Terms: Enkephalin, Methionine Preferred Term
Term UI T014499
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1983); Methionine Enkephalin
Term UI T014498
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX); Met(5)-Enkephalin
Term UI T014500
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX); Met-Enkephalin
Term UI T014501
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX); 5-Methionine Enkephalin
Term UI T014497
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Enkephalin, Methionine MeSH Descriptor Data 2025