MeSH Browser

MeSH Heading: Amifostine
Tree Number(s): D02.705.400.625.050; D02.705.539.345.050; D02.886.300.692.050
Unique ID: D004999
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004999
Scope Note: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Entry Term(s): APAETP; Amifostine Anhydrous; Amifostine Disodium Salt; Amifostine Monohydrate; Amifostine Monohydrochloride; Amifostine Trihydrate; Aminopropyl Aminoethylthiophosphate; Aminopropylaminoethylthiophosphate; Aminopropylaminoethylthiophosphoric Acid; Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate; Ethiofos; Ethiofos Anhydrous; Ethyol; Gammaphos; NSC-296961; S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid; WR-2721; YM-08310
Pharm Action: Radiation-Protective Agents
Registry Numbers: M487QF2F4V; 0; 104087-08-3; 59178-37-9; L693H6MM64; ILA426L95O
Related Numbers: 104087-08-3; 20537-88-6; 59178-37-9; 63717-27-1; ILA426L95O; L693H6MM64
CAS Type 1 Name: Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester)
Previous Indexing: Diamines (1974-1976); Organothiophosphorus Compounds (1972-1976)
Public MeSH Note: 1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Online Note: use AMIFOSTINE to search ETHIOFOS 1985-93 & WR 2721 1977-84
History Note: 1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Date Established: 1991/01/01
Date of Entry: 1976/04/13
Revision Date: 2018/05/30