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Amifostine
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Amifostine
Tree Number(s)
D02.705.400.625.050
D02.705.539.345.050
D02.886.300.692.050
Unique ID
D004999
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004999
Scope Note
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Entry Term(s)
APAETP
Amifostine Anhydrous
Amifostine Disodium Salt
Amifostine Monohydrate
Amifostine Monohydrochloride
Amifostine Trihydrate
Aminopropyl Aminoethylthiophosphate
Aminopropylaminoethylthiophosphate
Aminopropylaminoethylthiophosphoric Acid
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Ethiofos
Ethiofos Anhydrous
Ethyol
Gammaphos
NSC-296961
S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
WR-2721
YM-08310
Pharm Action
Radiation-Protective Agents
Registry Numbers
M487QF2F4V
0
104087-08-3
59178-37-9
L693H6MM64
ILA426L95O
Related Numbers
104087-08-3
20537-88-6
59178-37-9
63717-27-1
ILA426L95O
L693H6MM64
CAS Type 1 Name
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester)
Previous Indexing
Diamines (1974-1976)
Organothiophosphorus Compounds (1972-1976)
Public MeSH Note
1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Online Note
use AMIFOSTINE to search ETHIOFOS 1985-93 & WR 2721 1977-84
History Note
1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Date Established
1991/01/01
Date of Entry
1976/04/13
Revision Date
2018/05/30
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
analogs & derivatives (AA)
analysis (AN)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
Organic Chemicals [D02]
Organophosphorus Compounds [D02.705]
Organophosphates [D02.705.400]
Organothiophosphates [D02.705.400.625]
Amifostine [D02.705.400.625.050]
Azinphosmethyl [D02.705.400.625.060]
Chlorpyrifos [D02.705.400.625.100]
Coumaphos [D02.705.400.625.120]
Cystaphos [D02.705.400.625.130]
Diazinon [D02.705.400.625.200]
Dimethoate [D02.705.400.625.220]
Disulfoton [D02.705.400.625.230]
Echothiophate Iodide [D02.705.400.625.240]
Fenitrothion [D02.705.400.625.300]
Fenthion [D02.705.400.625.320]
Malathion [D02.705.400.625.500]
Parathion [D02.705.400.625.600]
Phorate [D02.705.400.625.650]
Phosmet [D02.705.400.625.670]
Temefos [D02.705.400.625.800]
Organic Chemicals [D02]
Organophosphorus Compounds [D02.705]
Organothiophosphorus Compounds [D02.705.539]
Organothiophosphates [D02.705.539.345]
Amifostine [D02.705.539.345.050]
Azinphosmethyl [D02.705.539.345.060]
Chlorpyrifos [D02.705.539.345.100]
Coumaphos [D02.705.539.345.120]
Cystaphos [D02.705.539.345.130]
Diazinon [D02.705.539.345.200]
Dimethoate [D02.705.539.345.220]
Disulfoton [D02.705.539.345.230]
Echothiophate Iodide [D02.705.539.345.240]
Fenitrothion [D02.705.539.345.300]
Fenthion [D02.705.539.345.320]
Malathion [D02.705.539.345.500]
Parathion [D02.705.539.345.600]
Phorate [D02.705.539.345.650]
Phosmet [D02.705.539.345.670]
Temefos [D02.705.539.345.800]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Organothiophosphorus Compounds [D02.886.300]
Organothiophosphates [D02.886.300.692]
Amifostine [D02.886.300.692.050]
Azinphosmethyl [D02.886.300.692.060]
Chlorpyrifos [D02.886.300.692.100]
Coumaphos [D02.886.300.692.120]
Cystaphos [D02.886.300.692.130]
Diazinon [D02.886.300.692.200]
Dimethoate [D02.886.300.692.220]
Disulfoton [D02.886.300.692.230]
Echothiophate Iodide [D02.886.300.692.240]
Fenitrothion [D02.886.300.692.300]
Fenthion [D02.886.300.692.320]
Malathion [D02.886.300.692.500]
Parathion [D02.886.300.692.600]
Phorate [D02.886.300.692.650]
Phosmet [D02.886.300.692.670]
Temefos [D02.886.300.692.800]
Expand All
Collapse All
Amifostine
Preferred
Concept UI
M0007867
Registry Numbers
M487QF2F4V
Related Numbers
104087-08-3
20537-88-6
59178-37-9
63717-27-1
ILA426L95O
L693H6MM64
Scope Note
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Terms
Amifostine
Preferred Term
Term UI
T015282
Date
01/01/1999
LexicalTag
NON
ThesaurusID
APAETP
Term UI
T015284
Date
09/18/1980
LexicalTag
ABB
ThesaurusID
UNK (19XX)
Aminopropylaminoethylthiophosphate
Narrower
Concept UI
M0007868
Registry Numbers
0
Terms
Aminopropylaminoethylthiophosphate
Preferred Term
Term UI
T015291
Date
11/20/1980
LexicalTag
NON
ThesaurusID
UNK (19XX)
Aminopropyl Aminoethylthiophosphate
Term UI
T015292
Date
11/20/1980
LexicalTag
NON
ThesaurusID
UNK (19XX)
Amifostine Monohydrochloride
Narrower
Concept UI
M0330363
Registry Numbers
104087-08-3
Terms
Amifostine Monohydrochloride
Preferred Term
Term UI
T360557
Date
09/13/1999
LexicalTag
NON
ThesaurusID
NLM (1999)
Amifostine Disodium Salt
Narrower
Concept UI
M0330364
Registry Numbers
59178-37-9
Terms
Amifostine Disodium Salt
Preferred Term
Term UI
T360558
Date
09/13/1999
LexicalTag
NON
ThesaurusID
NLM (1999)
Amifostine Monohydrate
Narrower
Concept UI
M0330365
Registry Numbers
L693H6MM64
Terms
Amifostine Monohydrate
Preferred Term
Term UI
T360559
Date
09/13/1999
LexicalTag
NON
ThesaurusID
YM-08310
Narrower
Concept UI
M0352162
Registry Numbers
0
Terms
YM-08310
Preferred Term
Term UI
T015290
Date
03/19/1980
LexicalTag
LAB
ThesaurusID
UNK (19XX)
WR-2721
Narrower
Concept UI
M0352163
Registry Numbers
0
Terms
WR-2721
Preferred Term
Term UI
T015289
Date
06/08/1984
LexicalTag
LAB
ThesaurusID
UNK (19XX)
NSC-296961
Narrower
Concept UI
M0352164
Registry Numbers
0
Terms
NSC-296961
Preferred Term
Term UI
T015287
Date
09/19/1984
LexicalTag
LAB
ThesaurusID
UNK (19XX)
Ethyol
Narrower
Concept UI
M0432472
Registry Numbers
0
Terms
Ethyol
Preferred Term
Term UI
T506566
Date
07/25/2002
LexicalTag
TRD
ThesaurusID
Amifostine Anhydrous
Narrower
Concept UI
M0585621
Registry Numbers
ILA426L95O
Terms
Amifostine Anhydrous
Preferred Term
Term UI
T845752
Date
06/17/2013
LexicalTag
NON
ThesaurusID
Ethiofos Anhydrous
Term UI
T845753
Date
06/17/2013
LexicalTag
TRD
ThesaurusID
Aminopropylaminoethylthiophosphoric Acid
Broader
Concept UI
M000623464
Registry Numbers
0
Terms
Aminopropylaminoethylthiophosphoric Acid
Preferred Term
Term UI
T015283
Date
09/18/1980
LexicalTag
NON
ThesaurusID
UNK (19XX)
S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
Term UI
T015288
Date
01/08/1981
LexicalTag
NON
ThesaurusID
UNK (19XX)
Ethiofos
Narrower
Concept UI
M000623467
Registry Numbers
0
Terms
Ethiofos
Preferred Term
Term UI
T015285
Date
08/31/1992
LexicalTag
TRD
ThesaurusID
Gammaphos
Narrower
Concept UI
M000623468
Registry Numbers
0
Terms
Gammaphos
Preferred Term
Term UI
T015286
Date
06/08/1984
LexicalTag
TRD
ThesaurusID
Amifostine Trihydrate
Narrower
Concept UI
M000638457
Registry Numbers
0
Terms
Amifostine Trihydrate
Preferred Term
Term UI
T845758
Date
06/17/2013
LexicalTag
NON
ThesaurusID
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Narrower
Concept UI
M000642421
Registry Numbers
0
Terms
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Preferred Term
Term UI
T000942131
Date
04/13/2018
LexicalTag
NON
ThesaurusID
NLM (2019)
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