MeSH Browser

MeSH Heading: Genes, Homeobox
Tree Number(s): G05.360.340.024.340.230.500
Unique ID: D005801
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005801
Scope Note: Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
Entry Term(s): Genes, Homeo Box; Genes, Homeotic; Homeo Box; Homeo Box Sequence; Homeo Boxes; Homeobox; Homeobox Sequence; Homeoboxes; Homeotic Genes; Hox Genes; Sequence, Homeo Box
NLM Classification #: QU 470
Previous Indexing: Alleles (1968-1975); Drosophila Melanogaster (1972-1986); Genes, Structural (1983-1986); Morphogenesis (1983-1986)
See Also: Homeodomain Proteins
Public MeSH Note: 95; was GENES, HOMEO BOX 1987-94
Online Note: use GENES, HOMEOBOX to search GENES, HOMEO BOX 1987-94
History Note: 95; was GENES, HOMEO BOX 1987-94
Date Established: 1987/01/01
Date of Entry: 1986/06/18
Revision Date: 2012/07/03

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0009090
Scope Note: Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
Terms: Genes, Homeobox Preferred Term
Term UI T017490
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1987); Genes, Homeo Box
Term UI T017487
Date09/16/1993
LexicalTag NON
ThesaurusID NLM (1995); Genes, Homeotic
Term UI T017488
Date06/18/1986
LexicalTag NON
ThesaurusID UNK (19XX); Homeotic Genes
Term UI T017489
Date06/18/1986
LexicalTag NON
ThesaurusID UNK (19XX); Hox Genes
Term UI T819327
Date03/12/2012
LexicalTag ABX
ThesaurusID NLM (2013)

Concept UI: M0009092
Terms: Homeo Box Sequence Preferred Term
Term UI T017495
Date09/16/1993
LexicalTag NON
ThesaurusID NLM (1995); Homeo Box
Term UI T017491
Date05/09/1987
LexicalTag NON
ThesaurusID NLM (1988); Homeo Boxes
Term UI T017492
Date10/12/1989
LexicalTag NON
ThesaurusID NLM (1990); Homeobox
Term UI T017493
Date09/16/1993
LexicalTag NON
ThesaurusID NLM (1995); Homeobox Sequence
Term UI T017497
Date09/16/1993
LexicalTag NON
ThesaurusID NLM (1995); Homeoboxes
Term UI T017494
Date09/16/1993
LexicalTag NON
ThesaurusID NLM (1995); Sequence, Homeo Box
Term UI T017496
Date05/11/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Genes, Homeobox MeSH Descriptor Data 2025