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Globosides MeSH Descriptor Data 2025


MeSH Heading
Globosides
Tree Number(s)
D02.065.313.425
D09.400.410.420.525.200.425
D10.390.470.675.200.425
D10.570.877.360.612.200.425
Unique ID
D005915
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005915
Annotation
/biosyn /‌physiol permitted
Scope Note
Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.
Entry Term(s)
Cytolipins
Lacto-N-neotetraosylceramide
Lacto-N-tetraosylceramide
Lactoneotetraosylceramide
Registry Numbers
0
Previous Indexing
Cerebrosides (1972-1978)
Glycolipids (1966-1978)
Glycosphingolipids (1975-1978)
Public MeSH Note
91; was see under GLYCOSPHINGOLIPIDS 1979-90
History Note
91(79); was see under GLYCOSPHINGOLIPIDS 1979-90
Date Established
1991/01/01
Date of Entry
1978/05/16
Revision Date
2006/07/05
Globosides Preferred
Cytolipins Narrower
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