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Hemoglobinuria, Paroxysmal MeSH Descriptor Data 2023


MeSH Heading
Hemoglobinuria, Paroxysmal
Tree Number(s)
C15.378.071.141.560
C15.378.190.625.460
Unique ID
D006457
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006457
Scope Note
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
Entry Term(s)
Marchiafava-Micheli Syndrome
Paroxysmal Cold Hemoglobinuria
Paroxysmal Hemoglobinuria
Paroxysmal Hemoglobinuria, Cold
Paroxysmal Hemoglobinuria, Nocturnal
Paroxysmal Nocturnal Hemoglobinuria
NLM Classification #
WJ 344
Public MeSH Note
78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77
Online Note
use HEMOGLOBINURIA, PAROXYSMAL to search MARCHIAFAVA-MICHELI SYNDROME 1966-77
History Note
78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77
Date Established
1978/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Hemoglobinuria, Paroxysmal Preferred
Paroxysmal Cold Hemoglobinuria Narrower
Paroxysmal Nocturnal Hemoglobinuria Narrower
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