MeSH Browser

MeSH Heading: Hemoglobinuria, Paroxysmal
Tree Number(s): C15.378.071.141.560; C15.378.190.625.460
Unique ID: D006457
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006457
Scope Note: A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
Entry Term(s): Marchiafava-Micheli Syndrome; Paroxysmal Cold Hemoglobinuria; Paroxysmal Hemoglobinuria; Paroxysmal Hemoglobinuria, Cold; Paroxysmal Hemoglobinuria, Nocturnal; Paroxysmal Nocturnal Hemoglobinuria
NLM Classification #: WJ 344
Public MeSH Note: 78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77
Online Note: use HEMOGLOBINURIA, PAROXYSMAL to search MARCHIAFAVA-MICHELI SYNDROME 1966-77
History Note: 78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77
Date Established: 1978/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

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psychology (PX)

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urine (UR)

veterinary (VE)

virology (VI)

Hemoglobinuria, Paroxysmal MeSH Descriptor Data 2023