MeSH Browser

MeSH Heading: Hirschsprung Disease
Tree Number(s): C06.198.439; C06.405.469.158.701.439; C16.131.314.439
Unique ID: D006627
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006627
Annotation: acquired megacolon = MEGACOLON
Scope Note: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
Entry Version: HIRSCHSPRUNG DIS
Entry Term(s): Aganglionic Megacolon; Aganglionosis, Colonic; Aganglionosis, Rectosigmoid Colon; Aganglionosis, Total Colonic; Colonic Aganglionosis; Congenital Intestinal Aganglionosis; Congenital Megacolon; Hirschsprung's Disease; Megacolon, Aganglionic; Megacolon, Congenital; Rectosigmoid Aganglionosis; Total Colonic Aganglionosis
NLM Classification #: WI 528
Previous Indexing: Megacolon (1966-1982)
Public MeSH Note: 83; was HIRSCHSPRUNG'S DISEASE see MEGACOLON 1963-82
Online Note: search MEGACOLON 1966-82
History Note: 83; was HIRSCHSPRUNG'S DISEASE see MEGACOLON 1963-82
Date Established: 1983/01/01
Date of Entry: 1982/04/27
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0010379
Scope Note: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
Terms: Hirschsprung Disease Preferred Term
Term UI T019944
Date01/01/1999
LexicalTag EPO
ThesaurusID; Aganglionic Megacolon
Term UI T811616
Date11/15/2011
LexicalTag NON
ThesaurusID; Congenital Megacolon
Term UI T019941
Date04/27/1982
LexicalTag NON
ThesaurusID; Hirschsprung's Disease
Term UI T019943
Date04/27/1982
LexicalTag EPO
ThesaurusID; Megacolon, Aganglionic
Term UI T811617
Date11/15/2011
LexicalTag NON
ThesaurusID; Megacolon, Congenital
Term UI T019942
Date04/27/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Concept UI: M0010380
Terms: Aganglionosis, Colonic Preferred Term
Term UI T019945
Date09/04/1990
LexicalTag NON
ThesaurusID NLM (1992); Aganglionosis, Total Colonic
Term UI T528678
Date12/18/2002
LexicalTag NON
ThesaurusID; Colonic Aganglionosis
Term UI T019946
Date09/04/1990
LexicalTag NON
ThesaurusID NLM (1992); Total Colonic Aganglionosis
Term UI T528677
Date12/18/2002
LexicalTag NON
ThesaurusID NLM (2004)

Hirschsprung Disease MeSH Descriptor Data 2025