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Kainic Acid MeSH Descriptor Data 2023


MeSH Heading
Kainic Acid
Tree Number(s)
D03.383.773.400
Unique ID
D007608
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007608
Annotation
an antinematodal agent & excitatory amino acid agonist
Scope Note
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.
Entry Term(s)
Digenic Acid
Kainate
Pharm Action
Antinematodal Agents
Excitatory Amino Acid Agonists
Registry Number
SIV03811UC
Related Numbers
487-79-6
CAS Type 1 Name
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-
Previous Indexing
Pyrrolidines (1966-1977)
See Also
Receptors, Kainic Acid
Public MeSH Note
86; was see under PYRROLIDINES 1978-85
History Note
86(78); was see under PYRROLIDINES 1978-85
Date Established
1986/01/01
Date of Entry
1977/04/22
Revision Date
2016/05/31
Kainic Acid Preferred
Kainate Narrower
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