MeSH Browser

MeSH Heading: Hyperlipoproteinemia Type I
Tree Number(s): C16.320.565.398.465; C18.452.584.500.500.644.237; C18.452.584.563.465; C18.452.648.398.465
Unique ID: D008072
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008072
Scope Note: An inherited condition due to a deficiency of either LIPOPROTEIN LIPASE or APOLIPOPROTEIN C-II (a lipase-activating protein). The lack of lipase activities results in inability to remove CHYLOMICRONS and TRIGLYCERIDES from the blood which has a creamy top layer after standing.
Entry Term(s): Apolipoprotein C-II Deficiency; Burger-Grutz Syndrome; C-II Anapolipoproteinemia; Chylomicronemia, Familial; Familial Fat-Induced Hypertriglyceridemia; Familial Hyperchylomicronemia; Familial Hyperlipoproteinemia Type 1; Familial LPL Deficiency; Familial Lipoprotein Lipase Deficiency; Hyperchylomicronemia, Familial; Hyperlipemia, Essential Familial; Hyperlipemia, Idiopathic, Burger-Grutz Type; Hyperlipoproteinemia Type Ia; Hyperlipoproteinemia Type Ib; Hyperlipoproteinemia, Type I; Hyperlipoproteinemia, Type Ia; Hyperlipoproteinemia, Type Ib; LIPD Deficiency; Lipase D Deficiency; Lipoprotein Lipase Deficiency; Lipoprotein Lipase Deficiency, Familial
Previous Indexing: Hyperlipidemia/familial & genetic (1966-1979)
See Also: Apolipoprotein C-II; Lipoprotein Lipase
Public MeSH Note: 2007; see LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL 1991-2006, see HYPERLIPOPROTEINEMIA 1980-1990
History Note: 2007 (1980)
Date Established: 1991/01/01
Date of Entry: 1979/04/23
Revision Date: 2021/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Metabolism, Inborn Errors [C16.320.565]
    - Lipid Metabolism, Inborn Errors [C16.320.565.398]

Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
  - Lipid Metabolism Disorders [C18.452.584]
    - Dyslipidemias [C18.452.584.500]
      - Hyperlipidemias [C18.452.584.500.500]
        
        Hyperlipoproteinemias [C18.452.584.500.500.644]
        
        Hyperlipoproteinemia Type I [C18.452.584.500.500.644.237]
        
        Hyperlipoproteinemia Type II [C18.452.584.500.500.644.475]
        
        Hyperlipoproteinemia Type III [C18.452.584.500.500.644.485]
        
        Hyperlipoproteinemia Type IV [C18.452.584.500.500.644.490]
        
        Hyperlipoproteinemia Type V [C18.452.584.500.500.644.495]

Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
  - Lipid Metabolism Disorders [C18.452.584]
    - Lipid Metabolism, Inborn Errors [C18.452.584.563]

Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
  - Metabolism, Inborn Errors [C18.452.648]
    - Lipid Metabolism, Inborn Errors [C18.452.648.398]

Hyperlipoproteinemia Type I Preferred

Apolipoprotein C-II Deficiency Narrower

Hyperlipoproteinemia Type I MeSH Descriptor Data 2025