MeSH Browser

MeSH Heading: Lipoproteins, VLDL
Tree Number(s): D10.532.599; D12.776.521.622
Unique ID: D008079
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008079
Annotation: hypoprebetalipoproteinemia = LIPOPROTEINS, VLDL /‌blood (IM) + HYPOLIPOPROTEINEMIAS (IM); /‌defic: consider also HYPOLIPOPROTEINEMIAS
Scope Note: A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Entry Term(s): Lipoprotein VLDL II; Lipoproteins, VLDL I; Lipoproteins, VLDL III; Lipoproteins, VLDL1; Lipoproteins, VLDL2; Lipoproteins, VLDL3; Pre-beta-Lipoprotein; Pre-beta-Lipoproteins; Prebeta-Lipoprotein; Prebeta-Lipoproteins; Very Low Density Lipoprotein; Very-Low-Density Lipoprotein; Very-Low-Density Lipoproteins
Previous Indexing: Lipoproteins (1966-1971)
Public MeSH Note: 74; VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1974-95
History Note: 74(72); VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1972-95
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Lipids [D10]
- Lipoproteins [D10.532]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Lipoproteins [D12.776.521]

Lipoproteins, VLDL Preferred

Concept UI: M0012596
Scope Note: A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Terms: Lipoproteins, VLDL Preferred Term
Term UI T024107
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1972); Pre-beta-Lipoproteins
Term UI T662309
Date12/16/2005
LexicalTag NON
ThesaurusID NLM (2007); Prebeta-Lipoproteins
Term UI T024108
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Very-Low-Density Lipoproteins
Term UI T024109
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Pre-beta-Lipoprotein
Term UI T000997717
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Prebeta-Lipoprotein
Term UI T000997718
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Very-Low-Density Lipoprotein
Term UI T000997719
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Very Low Density Lipoprotein
Term UI T000997716
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021)

Lipoproteins, VLDL2 Narrower

Lipoproteins, VLDL1 Narrower

Lipoproteins, VLDL3 Narrower

Lipoproteins, VLDL MeSH Descriptor Data 2025