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A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Entry Term(s)
Lipoprotein VLDL II
Lipoproteins, VLDL I
Lipoproteins, VLDL III
Lipoproteins, VLDL1
Lipoproteins, VLDL2
Lipoproteins, VLDL3
Pre-beta-Lipoprotein
Pre-beta-Lipoproteins
Prebeta-Lipoprotein
Prebeta-Lipoproteins
Very Low Density Lipoprotein
Very-Low-Density Lipoprotein
Very-Low-Density Lipoproteins
Registry Numbers
0
Previous Indexing
Lipoproteins (1966-1971)
Public MeSH Note
74; VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1974-95
History Note
74(72); VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1972-95
A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.