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Methylmalonyl-CoA Mutase MeSH Descriptor Data 2023


MeSH Heading
Methylmalonyl-CoA Mutase
Tree Number(s)
D08.811.399.520.625
Unique ID
D008765
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008765
Annotation
/defic: consider also METHYLMALONIC ACID /‌urine (IM) + AMINO ACID METABOLISM, INBORN ERRORS (IM)
Scope Note
An enzyme that catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A block in this enzymatic conversion leads to the metabolic disease, methylmalonic aciduria. EC 5.4.99.2.
Entry Term(s)
Methylmalonyl-CoA Isomerase
Registry Number
EC 5.4.99.2
Related Numbers
9023-90-9
CAS Type 1 Name
(R)-2-Methyl-3-oxopropanoyl-CoA CoA-carbonylmutase
Previous Indexing
Isomerases (1969-1974)
Malonates (1969-1974)
Public MeSH Note
91; was see under ISOMERASES 1975-90
History Note
91(75); was see under ISOMERASES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/11
Revision Date
2003/07/09
Methylmalonyl-CoA Mutase Preferred
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