MeSH Browser

MeSH Heading: Nordefrin
Tree Number(s): D02.092.311.830.400; D02.455.426.559.389.657.166.175.830.400
Unique ID: D008771
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008771
Scope Note: A norepinephrine derivative used as a vasoconstrictor agent.
Entry Term(s): 3,4-Dihydroxynorephedrine; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,R*)-(+,-)-Isomer; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,S*)-(+-)-Isomer; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,R*), (R*,R*)-Isomer; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,S*), (R*,R*)-Isomer; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,R*)-Isomer; 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,S*)-Isomer; Cobefrine; Corbadrine; Levonordefrin; Methylnorepinephrine; Neo-Cobefrin; Nordefrin Hydrochloride; Nordefrin Hydrochloride, (R*,R*)-(+,-)-Isomer; Nordefrin Hydrochloride, (R*,S*)-(+,-)-Isomer; Nordefrin Tartrate, (R*,R*), (R*,R*) Isomer; Nordefrin Tartrate, (R*,S*), (R*,R*) Isomer; Nordefrin, (R*,R*)-Isomer; Nordefrin, (R*,S*)-Isomer; Norephrine; alpha-Methylnoradrenaline; alpha-Methylnorepinephrine
Pharm Action: Vasoconstrictor Agents
Registry Number: R81X549E70
Related Numbers: 10390-18-8; 138-61-4; 16202-33-8; 16906-82-4; 17298-73-6; 20521-15-7; 20727-99-5; 23224-48-8; 53633-27-5; 53643-19-9; 53693-75-7; 61-96-1; 6209-47-8; 6539-57-7; 74812-63-8; 829-74-3; 829-75-4; NGO8K841ZV; V008L6478D
CAS Type 1 Name: 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-
Public MeSH Note: 91; was METHYLNOREPINEPHRINE see under NOREPINEPHRINE/analogs & derivatives 1975-90, see under NORMETANEPHRINE 1971-74, & see NORMETANEPHRINE 1966-70
Online Note: use NORDEFRIN to search METHYLNOREPINEPHRINE 1975-90; use NORMETANEPHRINE 1966-74
History Note: 91(75); was METHYLNOREPINEPHRINE see under NOREPINEPHRINE/analogs & derivatives 1975-90, see under NORMETANEPHRINE 1971-74, & see NORMETANEPHRINE 1966-70
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Amines [D02.092]
  - Catecholamines [D02.092.311]
    - Norepinephrine [D02.092.311.830]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Phenols [D02.455.426.559.389.657]
        
        Catechols [D02.455.426.559.389.657.166]
        
        Catecholamines [D02.455.426.559.389.657.166.175]
        
        Norepinephrine [D02.455.426.559.389.657.166.175.830]
        
        Droxidopa [D02.455.426.559.389.657.166.175.830.220]
        
        Nordefrin [D02.455.426.559.389.657.166.175.830.400]
        
        Normetanephrine [D02.455.426.559.389.657.166.175.830.700]

Nordefrin Preferred

Concept UI: M0013653
Registry Number: R81X549E70
Related Numbers: 10390-18-8; 138-61-4; 16202-33-8; 16906-82-4; 17298-73-6; 20521-15-7; 20727-99-5; 23224-48-8; 53633-27-5; 53643-19-9; 53693-75-7; 61-96-1; 6209-47-8; 6539-57-7; 74812-63-8; 829-74-3; 829-75-4; NGO8K841ZV; V008L6478D
Scope Note: A norepinephrine derivative used as a vasoconstrictor agent.
Terms: Nordefrin Preferred Term
Term UI T026134
Date01/01/1999
LexicalTag NON
ThesaurusID; alpha-Methylnoradrenaline
Term UI T026132
Date08/25/1980
LexicalTag NON
ThesaurusID UNK (19XX); Norephrine
Term UI T026136
Date11/13/1996
LexicalTag NON
ThesaurusID NLM (1998); 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol
Term UI T026135
Date11/13/1996
LexicalTag NON
ThesaurusID NLM (1998); 3,4-Dihydroxynorephedrine
Term UI T026131
Date02/04/1993
LexicalTag NON
ThesaurusID NLM (1994); alpha-Methylnorepinephrine
Term UI T026133
Date09/20/1984
LexicalTag NON
ThesaurusID UNK (19XX)

Corbadrine Related

Methylnorepinephrine Broader

Neo-Cobefrin Related

Nordefrin, (R*,S*)-Isomer Related

Nordefrin Hydrochloride, (R*,R*)-(+,-)-Isomer Narrower

Nordefrin Hydrochloride, (R*,S*)-(+,-)-Isomer Narrower

Nordefrin Tartrate, (R*,R*), (R*,R*) Isomer Narrower

Nordefrin Tartrate, (R*,S*), (R*,R*) Isomer Narrower

Nordefrin, (R*,R*)-Isomer Related

Cobefrine Narrower

Nordefrin Hydrochloride Narrower

Nordefrin MeSH Descriptor Data 2023