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Mitotane MeSH Descriptor Data 2021


MeSH Heading
Mitotane
Tree Number(s)
D02.455.526.439.681
Unique ID
D008939
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008939
Scope Note
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Entry Term(s)
Chloditan
Chlodithane
Khloditan
Lysodren
Mytotan
o,p-DDD
ortho,para-DDD
Pharm Action
Antineoplastic Agents, Hormonal
Registry Number
78E4J5IB5J
Related Numbers
53-19-0
CAS Type 1 Name
Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-
Previous Indexing
DDD/PD (1966-1972)
Public MeSH Note
73
History Note
73
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/01
Mitotane Preferred
Chlodithane Narrower
Lysodren Narrower
Chloditan Narrower
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