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Mixed Connective Tissue Disease MeSH Descriptor Data 2021


MeSH Heading
Mixed Connective Tissue Disease
Tree Number(s)
C17.300.540
Unique ID
D008947
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008947
Annotation
a specific disease entity; do not confuse with CONNECTIVE TISSUE DISEASES
Scope Note
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
Entry Version
MIXED CONNECTIVE TISSUE DIS
Entry Term(s)
Connective Tissue Disease, Mixed
MCTD
Sharp Syndrome
NLM Classification #
QZ 192
Previous Indexing
Collagen Diseases (1972-1978)
Lupus Erythematosus, Systemic (1972-1978)
Scleroderma, Systemic (1972-1978)
Public MeSH Note
79
History Note
79
Date Established
1979/01/01
Date of Entry
1978/05/15
Revision Date
2013/07/09
Mixed Connective Tissue Disease Preferred
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