MeSH Browser

MeSH Heading: Ipratropium
Tree Number(s): D02.145.074.722.229.400; D03.132.760.180.572.400; D03.132.889.180.648.400; D03.605.084.500.722.229.400; D03.605.869.229.400
Unique ID: D009241
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009241
Scope Note: A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
Entry Term(s): (endo,syn)-(+-)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane; Atrovent; Ipratropium Bromide; Ipratropium Bromide Anhydrous; Ipratropium Bromide Monohydrate; Ipratropium Bromide, (endo,anti)-Isomer; Ipratropium Bromide, (exo,syn)-Isomer; Ipratropium Bromide, endo-Isomer; Itrop; N-Isopropylatropine; Sch-1000; Sch-1178
Pharm Action: Bronchodilator Agents
Cholinergic Antagonists
Related Numbers: 22254-24-6; 24358-20-1; 58073-59-9; 60205-81-4; 60251-88-9; J697UZ2A9J; VJV4X1P2Z1
CAS Type 1 Name: 8-Azoniabicyclo(3.2.1)octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, (endo,syn)-(+-)-
Previous Indexing: Atropine (1973-1974); Propane (1973-1974)
Public MeSH Note: 93; was N-ISOPROPYLATROPINE 1975-92 (see under ATROPINE DERIVATIVES 1978-90, see under ATROPINE 1975-77); IPRATROPIUM BROMIDE was see N-ISOPROPYLATROPINE 1976-92
Online Note: use IPRATROPIUM to search N-ISOPROPYLATROPINE 1975-92 & IPRATROPIUM BROMIDE 1976-92
History Note: 93; was N-ISOPROPYLATROPINE 1975-92 (see under ATROPINE DERIVATIVES 1978-90 & see under ATROPINE 1975-77); IPRATROPIUM BROMIDE was see N-ISOPROPYLATROPINE 1976-92
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2018/02/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Aza Compounds [D02.145]
  - Azabicyclo Compounds [D02.145.074]
    - Tropanes [D02.145.074.722]
      - Atropine Derivatives [D02.145.074.722.229]
        
        Atropine [D02.145.074.722.229.199]
        
        Ipratropium [D02.145.074.722.229.400]
        
        Albuterol, Ipratropium Drug Combination [D02.145.074.722.229.400.500]

Heterocyclic Compounds [D03]
- Alkaloids [D03.132]
  - Solanaceous Alkaloids [D03.132.760]
    - Belladonna Alkaloids [D03.132.760.180]
      - Atropine Derivatives [D03.132.760.180.572]
        
        Atropine [D03.132.760.180.572.199]
        
        Ipratropium [D03.132.760.180.572.400]
        
        Albuterol, Ipratropium Drug Combination [D03.132.760.180.572.400.500]

Heterocyclic Compounds [D03]
- Alkaloids [D03.132]
  - Tropanes [D03.132.889]
    - Belladonna Alkaloids [D03.132.889.180]
      - Atropine Derivatives [D03.132.889.180.648]
        
        Atropine [D03.132.889.180.648.199]
        
        Ipratropium [D03.132.889.180.648.400]
        
        Albuterol, Ipratropium Drug Combination [D03.132.889.180.648.400.500]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Bridged-Ring [D03.605]
  - Bridged Bicyclo Compounds, Heterocyclic [D03.605.084]
    - Azabicyclo Compounds [D03.605.084.500]
      - Tropanes [D03.605.084.500.722]
        
        Atropine Derivatives [D03.605.084.500.722.229]
        
        Atropine [D03.605.084.500.722.229.199]
        
        Ipratropium [D03.605.084.500.722.229.400]
        
        Albuterol, Ipratropium Drug Combination [D03.605.084.500.722.229.400.500]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Bridged-Ring [D03.605]
  - Tropanes [D03.605.869]
    - Atropine Derivatives [D03.605.869.229]
      - Atropine [D03.605.869.229.199]
      - Ipratropium [D03.605.869.229.400]
        
        Albuterol, Ipratropium Drug Combination [D03.605.869.229.400.500]

Ipratropium Preferred

Concept UI: M0014399
Related Numbers: 22254-24-6; 24358-20-1; 58073-59-9; 60205-81-4; 60251-88-9; J697UZ2A9J; VJV4X1P2Z1
Scope Note: A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
Terms: Ipratropium Preferred Term
Term UI T027556
Date01/01/1999
LexicalTag NON
ThesaurusID; N-Isopropylatropine
Term UI T027557
Date04/05/1992
LexicalTag NON
ThesaurusID NLM (1993); (endo,syn)-(+-)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane
Term UI T027558
Date03/23/1994
LexicalTag NON
ThesaurusID NLM (1995)

Sch-1178 Narrower

Atrovent Narrower

Ipratropium Bromide Narrower

Ipratropium Bromide, endo-Isomer Narrower

Ipratropium Bromide, (endo,anti)-Isomer Narrower

Ipratropium Bromide, (exo,syn)-Isomer Narrower

Itrop Narrower

Ipratropium Bromide Anhydrous Narrower

Sch-1000 Narrower

Ipratropium Bromide Monohydrate Narrower

Ipratropium MeSH Descriptor Data 2025