- Concept UI
- M0014694
- Scope Note
- An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
- Terms
-
Neuritis, Autoimmune, Experimental
Preferred Term
Term UI
T586461
Date05/12/2004
LexicalTag
NON
ThesaurusID
NLM (2005)
-
Experimental Allergic Neuritis
Term UI
T028148
Date11/28/1990
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Neuritis, Experimental Allergic
Term UI
T028150
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1982)
-
Autoimmune Neuritis, Experimental
Term UI
T368157
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Experimental Autoimmune Neuritis
Term UI
T368169
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Allergic Neuritis, Experimental
Term UI
T028146
Date11/28/1990
LexicalTag
NON
ThesaurusID
NLM (1992)
-
EAN (Experimental Allergic Neuritis)
Term UI
T368171
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
EAN (Experimental Autoimmune Neuritis)
Term UI
T368172
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Neuritis, Experimental Autoimmune
Term UI
T368173
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Experimental Autoimmune Neuropathy
Term UI
T368170
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)