MeSH Browser

MeSH Heading: Neurosyphilis
Tree Number(s): C01.150.252.223.600; C01.150.252.400.794.840.500.750; C01.150.252.400.840.500.750; C01.207.180.600; C10.228.228.180.600
Unique ID: D009494
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009494
Scope Note: Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Entry Term(s): Central Nervous System Syphilis; General Paralysis; General Paralysis of the Insane; General Paresis; General Paresis of the Insane; Juvenile Paresis; Neurosyphilis, Asymptomatic; Neurosyphilis, Gummatous; Neurosyphilis, Juvenile; Neurosyphilis, Secondary; Neurosyphilis, Symptomatic; Paralysis, General; Paretic Neurosyphilis; Secondary Neurosyphilis; Syphilis, CNS; Syphilis, Central Nervous System
NLM Classification #: WC 165
Public MeSH Note: 1966; for GENERAL PARALYSIS & PARALYSIS, GENERAL see PARESIS 1963-93
History Note: 1963; for GENERAL PARALYSIS & PARALYSIS, GENERAL use PARESIS 1963-93
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/06/17

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

transmission (TM)

urine (UR)

veterinary (VE)

virology (VI)

Infections [C01]
- Bacterial Infections and Mycoses [C01.150]
  - Bacterial Infections [C01.150.252]
    - Central Nervous System Bacterial Infections [C01.150.252.223]

Infections [C01]
- Bacterial Infections and Mycoses [C01.150]
  - Bacterial Infections [C01.150.252]
    - Gram-Negative Bacterial Infections [C01.150.252.400]
      - Spirochaetales Infections [C01.150.252.400.794]
        
        Treponemal Infections [C01.150.252.400.794.840]
        
        Syphilis [C01.150.252.400.794.840.500]
        
        Chancre [C01.150.252.400.794.840.500.500]
        
        Neurosyphilis [C01.150.252.400.794.840.500.750]
        
        Tabes Dorsalis [C01.150.252.400.794.840.500.750.800]
        
        Syphilis, Cardiovascular [C01.150.252.400.794.840.500.875]
        
        Syphilis, Congenital [C01.150.252.400.794.840.500.937]
        
        Syphilis, Cutaneous [C01.150.252.400.794.840.500.968]
        
        Syphilis, Latent [C01.150.252.400.794.840.500.984]

Infections [C01]
- Bacterial Infections and Mycoses [C01.150]
  - Bacterial Infections [C01.150.252]
    - Gram-Negative Bacterial Infections [C01.150.252.400]
      - Treponemal Infections [C01.150.252.400.840]
        
        Syphilis [C01.150.252.400.840.500]
        
        Chancre [C01.150.252.400.840.500.500]
        
        Neurosyphilis [C01.150.252.400.840.500.750]
        
        Tabes Dorsalis [C01.150.252.400.840.500.750.800]
        
        Syphilis, Cardiovascular [C01.150.252.400.840.500.875]
        
        Syphilis, Congenital [C01.150.252.400.840.500.937]
        
        Syphilis, Cutaneous [C01.150.252.400.840.500.968]
        
        Syphilis, Latent [C01.150.252.400.840.500.984]

Infections [C01]
- Central Nervous System Infections [C01.207]
  - Central Nervous System Bacterial Infections [C01.207.180]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Central Nervous System Infections [C10.228.228]
    - Central Nervous System Bacterial Infections [C10.228.228.180]

Neurosyphilis Preferred

Concept UI: M0014771
Scope Note: Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Terms: Neurosyphilis Preferred Term
Term UI T028298
Date01/01/1999
LexicalTag NON
ThesaurusID; Syphilis, Central Nervous System
Term UI T369701
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Central Nervous System Syphilis
Term UI T369702
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Syphilis, CNS
Term UI T369713
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000)

General Paralysis Narrower

Concept UI: M0014772
Terms: General Paralysis Preferred Term
Term UI T028299
Date12/02/1992
LexicalTag NON
ThesaurusID NLM (1994); General Paralysis of the Insane
Term UI T000941597
Date03/27/2018
LexicalTag NON
ThesaurusID NLM (2019); Paralysis, General
Term UI T028300
Date12/02/1992
LexicalTag NON
ThesaurusID NLM (1994); General Paresis
Term UI T028301
Date12/02/1992
LexicalTag NON
ThesaurusID NLM (1994); Paretic Neurosyphilis
Term UI T028302
Date12/02/1992
LexicalTag NON
ThesaurusID NLM (1994); General Paresis of the Insane
Term UI T369703
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000)

Juvenile Paresis Narrower

Neurosyphilis, Asymptomatic Narrower

Neurosyphilis, Gummatous Narrower

Neurosyphilis, Juvenile Narrower

Neurosyphilis, Secondary Narrower

Neurosyphilis, Symptomatic Narrower

Neurosyphilis MeSH Descriptor Data 2025