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Phenobarbital MeSH Descriptor Data 2021


MeSH Heading
Phenobarbital
Tree Number(s)
D03.383.742.698.253.650
Unique ID
D010634
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010634
Scope Note
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Entry Term(s)
Gardenal
Hysteps
Luminal
Phenemal
Phenobarbital Sodium
Phenobarbital, Monosodium Salt
Phenobarbitone
Phenylbarbital
Phenylethylbarbituric Acid
Pharm Action
Anticonvulsants
Hypnotics and Sedatives
Excitatory Amino Acid Antagonists
GABA Modulators
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 CYP3A Inducers
Registry Number
YQE403BP4D
Related Numbers
50-06-6
57-30-7
SW9M9BB5K3
CAS Type 1 Name
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-
NLM Classification #
QV 88
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/31
Phenobarbital Preferred
Hysteps Narrower
Phenobarbital Sodium Narrower
Luminal Narrower
Gardenal Narrower
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