MeSH Browser

MeSH Heading: Poly I-C
Tree Number(s): D13.695.578.550.560.600; D13.695.578.550.650.600
Unique ID: D011070
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011070
Annotation: do not confuse with POLY I
Scope Note: Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
Entry Term(s): Poly(I-C); Poly(rI).Poly(rC); Polyinosinic-Polycytidylic Acid; Polyinosinic-Polycytidylic Acid (High MW); Polyriboinosinic-Polyribocytidylic Acid; Polyribose Inosin-Cytidil
Pharm Action: Antiviral Agents
Interferon Inducers
Related Numbers: 24939-03-5
CAS Type 1 Name: 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1)
Previous Indexing: Interferons/biosynthesis (1966-1970); Polynucleotides (1966-1970)
Public MeSH Note: 73
History Note: 73(71)
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/03/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0017148
Related Numbers: 24939-03-5
Scope Note: Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
Terms: Poly I-C Preferred Term
Term UI T032559
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1971); Poly(I-C)
Term UI T000911764
Date11/16/2016
LexicalTag NON
ThesaurusID NLM (2016); Polyriboinosinic-Polyribocytidylic Acid
Term UI T000911765
Date11/16/2016
LexicalTag NON
ThesaurusID NLM (2016); Polyinosinic-Polycytidylic Acid (High MW)
Term UI T000911763
Date11/16/2016
LexicalTag NON
ThesaurusID FDA SRS (2018); Poly(rI).Poly(rC)
Term UI T032560
Date12/02/1986
LexicalTag NON
ThesaurusID UNK (19XX); Polyinosinic-Polycytidylic Acid
Term UI T032561
Date07/13/1981
LexicalTag NON
ThesaurusID UNK (19XX); Polyribose Inosin-Cytidil
Term UI T032562
Date06/08/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Poly I-C MeSH Descriptor Data 2025