MeSH Browser

MeSH Heading: Pregnenolone Carbonitrile
Tree Number(s): D02.626.745; D04.210.500.745.745.725.703
Unique ID: D011285
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011285
Scope Note: A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the potential for protective capability against acetaminophen-induced liver damage.
Entry Term(s): PCN; Pregnenolone 16 alpha-Carbonitrile; Pregnenolone Carbonitrile, (3 beta)-Isomer; Pregnenolone Carbonitrile, (3 beta,16 beta)-Isomer
Registry Numbers: 1434-54-4; 95341-23-4; 95721-74-7
Related Numbers: 95341-23-4; 95721-74-7
CAS Type 1 Name: Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3beta,16alpha)-
Public MeSH Note: 74
History Note: 74
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0017517
Registry Numbers: 1434-54-4
Related Numbers: 95341-23-4; 95721-74-7
Scope Note: A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the potential for protective capability against acetaminophen-induced liver damage.
Terms: Pregnenolone Carbonitrile Preferred Term
Term UI T033260
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1974); PCN
Term UI T033259
Date12/26/1978
LexicalTag ABB
ThesaurusID UNK (19XX); Pregnenolone 16 alpha-Carbonitrile
Term UI T033261
Date07/13/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Pregnenolone Carbonitrile MeSH Descriptor Data 2025