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Progeria MeSH Descriptor Data 2023


MeSH Heading
Progeria
Tree Number(s)
C16.320.488.875
C16.320.565.753
C18.452.648.753
Unique ID
D011371
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011371
Scope Note
An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.
Entry Term(s)
Hutchinson Gilford Progeria Syndrome
Hutchinson-Gilford Progeria Syndrome
Hutchinson-Gilford Syndrome
NLM Classification #
WS 104
See Also
Cockayne Syndrome
Werner Syndrome
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2020/02/21
Progeria Preferred
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