- Concept UI
- M0017884
- Registry Numbers
- EC 2.3.2.13
- Related Numbers
- 80146-85-6
- Scope Note
- Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
- Terms
-
Transglutaminases
Preferred Term
Term UI
T033991
Date04/24/1985
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Transglutaminase
Term UI
T000999603
Date11/26/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
-
Glutaminyl-Peptide Gamma-Glutamyltransferases
Term UI
T033989
Date04/24/1985
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Protein-Glutamine gamma-Glutamyltransferases
Term UI
T033990
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1986)