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Pyruvate Carboxylase MeSH Descriptor Data 2025


MeSH Heading
Pyruvate Carboxylase
Tree Number(s)
D08.811.464.257.500
Unique ID
D011766
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011766
Scope Note
A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.
Related Numbers
9014-19-1
CAS Type 1 Name
Pyruvate:carbon-dioxide ligase (ADP-forming)
See Also
Pyruvate Carboxylase Deficiency Disease
Public MeSH Note
74
History Note
74
Entry Combination
deficiency:Pyruvate Carboxylase Deficiency Disease
Date Established
1974/01/01
Date of Entry
1999/01/01
Revision Date
2010/06/25
Pyruvate Carboxylase Preferred
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