MeSH Browser

MeSH Heading: Safrole
Tree Number(s): D02.455.426.559.389.012.500; D03.383.246.118.750; D03.633.100.115.750
Unique ID: D012451
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012451
Scope Note: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
Entry Term(s): 4-Allyl-1,2-methylenedioxybenzene; Safrol; Shikimol
Related Numbers: 94-59-7
CAS Type 1 Name: 1,3-Benzodioxole, 5-(2-propenyl)-
Previous Indexing: Allyl Compounds (1972-1974); Dioxoles (1969-1974)
Public MeSH Note: 91; was see under DIOXOLES 1975-90
History Note: 91(75); was see under DIOXOLES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2019/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Safrole MeSH Descriptor Data 2025