MeSH Browser

MeSH Heading: Spleen Focus-Forming Viruses
Tree Number(s): B04.613.807.375.525.850; B04.820.650.375.525.850
Unique ID: D013155
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013155
Annotation: infection: coordinate IM with RETROVIRIDAE INFECTIONS (IM) + TUMOR VIRUS INFECTIONS (IM) + LEUKEMIA, EXPERIMENTAL (IM) or LEUKEMIA, ERYTHROBLASTIC, ACUTE (IM) (for spontaneous erythroleukemia)
Scope Note: Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.
Entry Term(s): Friend spleen focus-forming virus; Rauscher Spleen Focus-Forming Virus; SFFV
Related Numbers: txid11820; txid11821
Previous Indexing: Friend Virus (1966-1985); Leukemia, Experimental (1966-1985); Mouse Leukemia Viruses (1966-1985)
Public MeSH Note: 91; was see under MOUSE LEUKEMIA VIRUSES 1986-90
History Note: 91(86); was see under MOUSE LEUKEMIA VIRUSES 1986-90
Date Established: 1991/01/01
Date of Entry: 1985/05/09
Revision Date: 2020/08/13

Allowable Qualifiers: chemistry (CH)

classification (CL)

drug effects (DE)

enzymology (EN)

genetics (GE)

growth & development (GD)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pathogenicity (PY)

physiology (PH)

radiation effects (RE)

ultrastructure (UL)

Spleen Focus-Forming Viruses MeSH Descriptor Data 2025