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Sulbactam MeSH Descriptor Data 2021


MeSH Heading
Sulbactam
Tree Number(s)
D02.065.589.099.750.812
D02.886.108.750.812
D03.633.100.300.750.812
Unique ID
D013407
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013407
Scope Note
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
Entry Term(s)
B├ętamaze
CP-45899
Combactam
Penicillanic Acid Sulfone
Sulbactam Sodium
Pharm Action
Anti-Bacterial Agents
beta-Lactamase Inhibitors
Registry Number
S4TF6I2330
Related Numbers
68373-14-8
69388-84-7
DKQ4T82YE6
CAS Type 1 Name
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S-cis)-
NLM Classification #
QV 354
Previous Indexing
Beta Lactamases/antagonists & inhibitors (1979-1987)
Enzyme Inhibitors (1975-1987)
Enzymes/antagonists & inhibitors (1966-1974)
Penicillanic Acids (1971-1987)
Public MeSH Note
88
History Note
88
Date Established
1988/01/01
Date of Entry
1987/04/09
Revision Date
2017/05/24
Sulbactam Preferred
CP-45899 Narrower
Sulbactam Sodium Narrower
Combactam Narrower
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