MeSH Browser

MeSH Heading: Thromboxane-A Synthase
Tree Number(s): D08.811.399.475.900
Unique ID: D013930
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013930
Annotation: found in platelet microsomes
Scope Note: An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5.
Entry Term(s): Thromboxane A Synthase; Thromboxane A2 Synthetase; Thromboxane Synthetase
Registry Numbers: EC 5.3.99.5
Related Numbers: 60832-04-4
CAS Type 1 Name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A(2)-isomerase
Previous Indexing: Hydroxy Acids (1975-1977); Oxidoreductases (1966-1977); Pyrans (1966-1977)
Public MeSH Note: 98; see THROMBOXANE SYNTHETASE 1986-97; see OXIDOREDUCTASES 1978-85
History Note: 98(78)
Date Established: 1986/01/01
Date of Entry: 1977/05/24
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0021440
Registry Numbers: EC 5.3.99.5
Related Numbers: 60832-04-4
Scope Note: An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5.
Terms: Thromboxane-A Synthase Preferred Term
Term UI T040860
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1978); Thromboxane A Synthase
Term UI T040859
Date06/10/1985
LexicalTag NON
ThesaurusID UNK (19XX); Thromboxane A2 Synthetase
Term UI T040861
Date08/10/1987
LexicalTag NON
ThesaurusID UNK (19XX); Thromboxane Synthetase
Term UI T040862
Date11/08/1996
LexicalTag NON
ThesaurusID NLM (1998)

Thromboxane-A Synthase MeSH Descriptor Data 2025