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Tissue Distribution MeSH Descriptor Data 2023


MeSH Heading
Tissue Distribution
Tree Number(s)
G03.787.917
G07.690.725.949
Unique ID
D014018
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014018
Annotation
general only: not a substitute for organ /‌metab or organ /‌chem; usually NIM; coordinate with substance /‌pharmacokin or /‌metab
Scope Note
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
NLM Classification #
QV 38
Previous Indexing
Organ Specificity (1966-1977)
Public MeSH Note
78
History Note
78
Date Established
1978/01/01
Date of Entry
1977/04/27
Revision Date
2016/07/01
Tissue Distribution Preferred
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