MeSH Browser

MeSH Heading: 2-Aminoadipic Acid
Tree Number(s): D02.241.081.337.052.075; D12.125.119.075
Unique ID: D015074
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015074
Scope Note: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
Entry Term(s): 2 Aminoadipic Acid; 2-Aminohexanedioic Acid; alpha-Aminoadipic Acid
Pharm Action: Excitatory Amino Acid Antagonists
Related Numbers: 542-32-5
CAS Type 1 Name: Hexanedioic acid, 2-amino-
Previous Indexing: Adipic Acids (1969-1975); Amino Acids, Dicarboxylic (1974-1975)
Public MeSH Note: 91; was see under AMINO ACIDS, DICARBOXYLIC 1976-90
History Note: 91(76); was see under AMINO ACIDS, DICARBOXYLIC 1976-90
Date Established: 1991/01/01
Date of Entry: 1975/07/21
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0023188
Related Numbers: 542-32-5
Scope Note: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
Terms: 2-Aminoadipic Acid Preferred Term
Term UI T043976
Date01/01/1999
LexicalTag NON
ThesaurusID; 2 Aminoadipic Acid
Term UI T043975
Date01/13/1978
LexicalTag NON
ThesaurusID UNK (19XX); 2-Aminohexanedioic Acid
Term UI T043977
Date08/26/1980
LexicalTag NON
ThesaurusID UNK (19XX); alpha-Aminoadipic Acid
Term UI T043978
Date05/17/1976
LexicalTag NON
ThesaurusID UNK (19XX)

2-Aminoadipic Acid MeSH Descriptor Data 2025