MeSH Browser

MeSH Heading: Gene Rearrangement, B-Lymphocyte, Light Chain
Tree Number(s): G05.344.401.601; G12.500.274.601
Unique ID: D015328
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015328
Scope Note: Ordered rearrangement of B-lymphocyte variable gene regions coding for the kappa or lambda IMMUNOGLOBULIN LIGHT CHAINS, thereby contributing to antibody diversity. It occurs during the second stage of differentiation of the IMMATURE B-LYMPHOCYTES.
Entry Version: GENE REARR LIGHT CHAIN
Entry Term(s): B Cell Light Chain Gene Rearrangement; B Cell kappa-Chain Gene Rearrangement; B Cell lambda-Chain Gene Rearrangement; B Lymphocyte Light Chain Gene Rearrangement; B-Cell Light Chain Gene Rearrangement; B-Lymphocyte Light Chain Gene Rearrangement; B-Lymphocyte kappa-Chain Gene Rearrangement; B-Lymphocyte lambda-Chain Gene Rearrangement
Previous Indexing: B Lymphocytes/immunology (1977-1988); DNA/genetics (1977-1988); Genes, Immunoglobulin (1977-1988); Immunoglobulins, Light Chain/genetics (1977-1988)
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/06/01
Revision Date: 2016/06/23

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Gene Rearrangement, B-Lymphocyte, Light Chain MeSH Descriptor Data 2025