MeSH Browser

MeSH Heading: Giant Cells, Foreign-Body
Tree Number(s): A11.329.372.376; A11.500.376; A11.627.482.376; A11.733.397.376; A15.382.670.522.376; A15.382.680.397.376
Unique ID: D015743
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015743
Scope Note: Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells (GIANT CELLS, LANGHANS), but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm.
Entry Term(s): Foreign Body Giant Cell; Foreign Body Giant Cells; Foreign Body-Type Giant Cells
Previous Indexing: Foreign Body Reaction (1972-1989); Macrophages (1966-1989)
Public MeSH Note: 91; was see under GIANT CELLS 1990
History Note: 91(90); was see under GIANT CELLS 1990
Date Established: 1991/01/01
Date of Entry: 1989/04/07
Revision Date: 2018/06/30

Allowable Qualifiers: chemistry (CH)

classification (CL)

cytology (CY)

drug effects (DE)

enzymology (EN)

immunology (IM)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

radiation effects (RE)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Concept UI: M0024132
Scope Note: Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells (GIANT CELLS, LANGHANS), but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm.
Terms: Giant Cells, Foreign-Body Preferred Term
Term UI T046702
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); Foreign Body-Type Giant Cells
Term UI T046699
Date02/27/1989
LexicalTag NON
ThesaurusID NLM (1990); Foreign Body Giant Cell
Term UI T046700
Date02/27/1989
LexicalTag NON
ThesaurusID NLM (1990); Foreign Body Giant Cells
Term UI T046701
Date02/27/1989
LexicalTag NON
ThesaurusID NLM (1990)

Giant Cells, Foreign-Body MeSH Descriptor Data 2025