MeSH Browser

MeSH Heading: Eukaryotic Initiation Factor-2
Tree Number(s): D12.776.835.725.868.249
Unique ID: D015852
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015852
Scope Note: Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three subunits: alpha, beta, and gamma. As initiation proceeds, eIF-2 forms a ternary complex with Met-tRNAi and GTP.
Entry Term(s): EIF-2; EIF-2 alpha; EIF-2 beta; EIF-2 gamma; EIF-2alpha; EIF-2beta; EIF-2gamma; EIF2; Eukaryotic Initiation Factor-2, alpha Subunit; Eukaryotic Initiation Factor-2, beta Subunit; Eukaryotic Initiation Factor-2, gamma Subunit; Eukaryotic Peptide Initiation Factor-2; Peptide Initiation Factor EIF-2
Registry Numbers: 0
Previous Indexing: Peptide Initiation Factors (1978-1989)
Public MeSH Note: 2003; see EIF-2 1990-2002
History Note: 2003(1990)
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2002/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024274
Registry Numbers: 0
Scope Note: Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three subunits: alpha, beta, and gamma. As initiation proceeds, eIF-2 forms a ternary complex with Met-tRNAi and GTP.
Terms: Eukaryotic Initiation Factor-2 Preferred Term
Term UI T047032
Date05/25/1989
LexicalTag NON
ThesaurusID NLM (1990); EIF-2
Term UI T047031
Date01/01/1999
LexicalTag ABX
ThesaurusID NLM (1990); Eukaryotic Peptide Initiation Factor-2
Term UI T489241
Date04/11/2002
LexicalTag NON
ThesaurusID NLM (2003); Peptide Initiation Factor EIF-2
Term UI T047033
Date05/10/1989
LexicalTag NON
ThesaurusID NLM (1990); EIF2
Term UI T047034
Date03/24/1989
LexicalTag NON
ThesaurusID NLM (1990)

Eukaryotic Initiation Factor-2 MeSH Descriptor Data 2025