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Methacholine Chloride MeSH Descriptor Data 2023


MeSH Heading
Methacholine Chloride
Tree Number(s)
D02.092.877.883.555.500
D02.675.276.534.500
Unique ID
D016210
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016210
Scope Note
A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
Entry Term(s)
2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride
Acetyl-2-methylcholine Chloride
Acetyl-beta-methacholine Chloride
Acetyl-beta-methylcholine
Mecholine
Mecholyl
Methacholine
Provocholine
Provokit
Pharm Action
Miotics
Parasympathomimetics
Bronchoconstrictor Agents
Muscarinic Agonists
Registry Number
0W5ETF9M2K
Related Numbers
03V657ZD3V
55-92-5
62-51-1
CAS Type 1 Name
1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride
Previous Indexing
Methacholine Compounds (1966-1990)
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/04/24
Revision Date
2016/07/01
Methacholine Chloride Preferred
Mecholyl Broader
Provocholine Narrower
Provokit Narrower
Acetyl-beta-methylcholine Broader
Methacholine Broader
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