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Rioprostil MeSH Descriptor Data 2023


MeSH Heading
Rioprostil
Tree Number(s)
D10.251.355.255.550.775.450.750
D23.469.050.175.725.775.450.750
D23.469.700.660.750
Unique ID
D016630
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016630
Scope Note
A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.
Entry Term(s)
ORF-15927
RWJ-15927
TR-4698
Pharm Action
Anti-Ulcer Agents
Registry Number
7JL402PVQR
Related Numbers
77287-05-9
CAS Type 1 Name
Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)-
Previous Indexing
Anti-Ulcer Agents (1977-1991)
Prostaglandins E (1975-1991)
Prostaglandins, Synthetic (1977-1991)
Public MeSH Note
92; RIOPROSTIL was indexed under PROSTAGLANDINS E 1985-91
Online Note
use RIOPROSTIL (NM) to search RIOPROSTIL 1985-91
History Note
92; was RIOPROSTIL (NM) 1985-91
Date Established
1992/01/01
Date of Entry
1991/01/25
Revision Date
2015/06/08
Rioprostil Preferred
TR-4698 Narrower
ORF-15927 Narrower
RWJ-15927 Narrower
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