- Concept UI
- M0025348
- Registry Numbers
- 0
- Scope Note
- The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
- Terms
-
Apolipoprotein A-I
Preferred Term
Term UI
T049785
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Apo A-I
Term UI
T049784
Date10/31/1990
LexicalTag
ABB
ThesaurusID
NLM (1992)
-
Apo A1
Term UI
T049789
Date12/24/1990
LexicalTag
ABB
ThesaurusID
NLM (1992)
-
Apo AI
Term UI
T049791
Date11/28/1990
LexicalTag
ABB
ThesaurusID
NLM (1992)
-
ApoA-1
Term UI
T049788
Date12/24/1990
LexicalTag
ABB
ThesaurusID
NLM (1992)
-
ApoA-I
Term UI
T049793
Date10/31/1990
LexicalTag
ABB
ThesaurusID
NLM (1992)
-
Apolipoprotein A-1
Term UI
T049787
Date12/24/1990
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Apolipoprotein A1
Term UI
T049790
Date12/24/1990
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Apo A-1
Term UI
T049786
Date12/24/1990
LexicalTag
ABB
ThesaurusID
NLM (1992)
-
Apolipoprotein AI
Term UI
T049792
Date10/31/1990
LexicalTag
NON
ThesaurusID
NLM (1992)