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Monocrotaline MeSH Descriptor Data 2023


MeSH Heading
Monocrotaline
Tree Number(s)
D03.132.716.500
D03.633.100.772.500
Unique ID
D016686
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016686
Scope Note
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
Entry Term(s)
Monocrotaline Hydrochloride (13alpha,14alpha)-Isomer
Monocrotaline, (all-xi)-Isomer
Registry Number
73077K8HYV
Related Numbers
315-22-0
83114-75-4
901-82-6
CAS Type 1 Name
20-Norcrotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-, (13alpha,14alpha)-
Previous Indexing
Pyrrolizidine Alkaloids (1971-1973)
Public MeSH Note
92; MONOCROTALINE was indexed under PYRROLIZIDINE ALKALOIDS 1973-91
Online Note
use MONOCROTALINE (NM) to search MONOCROTALINE 1980-91
History Note
92; was MONOCROTALINE (NM) 1973-91
Date Established
1992/01/01
Date of Entry
1991/01/25
Revision Date
2016/05/31
Monocrotaline Preferred
Monocrotaline Hydrochloride (13alpha,14alpha)-Isomer Narrower
Monocrotaline, (all-xi)-Isomer Narrower
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