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Bone Remodeling MeSH Descriptor Data 2023


MeSH Heading
Bone Remodeling
Tree Number(s)
G11.427.213
G16.762.150
Unique ID
D016723
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016723
Annotation
note category: an aspect of bone physiol
Scope Note
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Entry Term(s)
Bone Turnover
NLM Classification #
WE 202
Previous Indexing
Bone Development (1967-1991)
Bone Regeneration (1967-1991)
Bone Resorption (1967-1991)
Public MeSH Note
92
History Note
92
Date Established
1992/01/01
Date of Entry
1991/04/29
Revision Date
2016/06/02
Bone Remodeling Preferred
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