- Concept UI
- M0026633
- Registry Numbers
- 0
- Scope Note
- (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
- Terms
-
Leukotriene A4
Preferred Term
Term UI
T052688
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1994)
-
LTA4
Term UI
T052689
Date06/09/1992
LexicalTag
ABB
ThesaurusID
NLM (1993)
-
Leukotriene A-4
Term UI
T052690
Date05/10/1993
LexicalTag
NON
ThesaurusID
NLM (1994)