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CREST Syndrome
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
CREST Syndrome
Tree Number(s)
C06.405.117.119.500.204
C14.907.355.830.573.750.500
C14.907.617.812.500
C14.907.823.225
C17.300.799.801.500
C17.800.784.801.500
C17.800.862.406.750.500
C18.452.174.130.204
Unique ID
D017675
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017675
Annotation
CREST syndrome: an acronym for Calcinosis, Raynaud phenomenon, Esophageal dysfunction, Sclerodactyly, Telangiectasis
Scope Note
A mild form of
LIMITED SCLERODERMA
, a multi-system disorder. Its features include symptoms of
CALCINOSIS
;
RAYNAUD DISEASE
;
ESOPHAGEAL MOTILITY DISORDERS
; sclerodactyly, and
TELANGIECTASIS
. When the defect in esophageal function is not prominent, it is known as CRST syndrome.
Entry Term(s)
CRST Syndrome
Calcinosis, Raynaud's phenomenon, Esophageal dismobility, Sclerodactyly, Telangiectasia Syndrome
Calcinosis-Raynaud Phenomenon-Sclerodactyly-Telangiectasia
Previous Indexing
Calcinosis (1975-1993)
Raynaud's Disease (1975-1993)
Scleroderma, Systemic (1975-1993)
Public MeSH Note
1994
History Note
1994
Date Established
1994/01/01
Date of Entry
1992/12/28
Revision Date
2021/10/18
Allowable Qualifiers
blood (BL)
cerebrospinal fluid (CF)
chemically induced (CI)
classification (CL)
complications (CO)
congenital (CN)
diagnosis (DI)
diagnostic imaging (DG)
diet therapy (DH)
drug therapy (DT)
economics (EC)
embryology (EM)
enzymology (EN)
epidemiology (EP)
ethnology (EH)
etiology (ET)
genetics (GE)
history (HI)
immunology (IM)
metabolism (ME)
microbiology (MI)
mortality (MO)
nursing (NU)
parasitology (PS)
pathology (PA)
physiopathology (PP)
prevention & control (PC)
psychology (PX)
radiotherapy (RT)
rehabilitation (RH)
surgery (SU)
therapy (TH)
urine (UR)
veterinary (VE)
virology (VI)
Digestive System Diseases [C06]
Gastrointestinal Diseases [C06.405]
Esophageal Diseases [C06.405.117]
Deglutition Disorders [C06.405.117.119]
Esophageal Motility Disorders [C06.405.117.119.500]
CREST Syndrome [C06.405.117.119.500.204]
Esophageal Achalasia [C06.405.117.119.500.432]
Esophageal Spasm, Diffuse [C06.405.117.119.500.450]
Gastroesophageal Reflux [C06.405.117.119.500.484]
Plummer-Vinson Syndrome [C06.405.117.119.500.742]
Cardiovascular Diseases [C14]
Vascular Diseases [C14.907]
Embolism and Thrombosis [C14.907.355]
Thrombosis [C14.907.355.830]
Livedoid Vasculopathy [C14.907.355.830.573]
Raynaud Disease [C14.907.355.830.573.750]
CREST Syndrome [C14.907.355.830.573.750.500]
Cardiovascular Diseases [C14]
Vascular Diseases [C14.907]
Peripheral Vascular Diseases [C14.907.617]
Raynaud Disease [C14.907.617.812]
CREST Syndrome [C14.907.617.812.500]
Cardiovascular Diseases [C14]
Vascular Diseases [C14.907]
Telangiectasis [C14.907.823]
Ataxia Telangiectasia [C14.907.823.213]
CREST Syndrome [C14.907.823.225]
Retinal Telangiectasis [C14.907.823.502]
Telangiectasia, Hereditary Hemorrhagic [C14.907.823.780]
Skin and Connective Tissue Diseases [C17]
Connective Tissue Diseases [C17.300]
Scleroderma, Systemic [C17.300.799]
Scleroderma, Limited [C17.300.799.801]
CREST Syndrome [C17.300.799.801.500]
Skin and Connective Tissue Diseases [C17]
Skin Diseases [C17.800]
Scleroderma, Systemic [C17.800.784]
Scleroderma, Limited [C17.800.784.801]
CREST Syndrome [C17.800.784.801.500]
Skin and Connective Tissue Diseases [C17]
Skin Diseases [C17.800]
Skin Diseases, Vascular [C17.800.862]
Livedoid Vasculopathy [C17.800.862.406]
Raynaud Disease [C17.800.862.406.750]
CREST Syndrome [C17.800.862.406.750.500]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Calcium Metabolism Disorders [C18.452.174]
Calcinosis [C18.452.174.130]
Calcinosis Cutis [C18.452.174.130.093]
Calciphylaxis [C18.452.174.130.186]
CREST Syndrome [C18.452.174.130.204]
Nephrocalcinosis [C18.452.174.130.560]
Vascular Calcification [C18.452.174.130.780]
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CREST Syndrome
Preferred
Concept UI
M0026732
Scope Note
A mild form of
LIMITED SCLERODERMA
, a multi-system disorder. Its features include symptoms of
CALCINOSIS
;
RAYNAUD DISEASE
;
ESOPHAGEAL MOTILITY DISORDERS
; sclerodactyly, and
TELANGIECTASIS
. When the defect in esophageal function is not prominent, it is known as CRST syndrome.
Terms
CREST Syndrome
Preferred Term
Term UI
T052879
Date
01/01/1999
LexicalTag
ACX
ThesaurusID
Calcinosis, Raynaud's phenomenon, Esophageal dismobility, Sclerodactyly, Telangiectasia Syndrome
Term UI
T751301
Date
05/15/2009
LexicalTag
EPO
ThesaurusID
NLM (2010)
CRST Syndrome
Narrower
Concept UI
M0026731
Terms
CRST Syndrome
Preferred Term
Term UI
T052878
Date
08/03/1992
LexicalTag
NON
ThesaurusID
NLM (1994)
Calcinosis-Raynaud Phenomenon-Sclerodactyly-Telangiectasia
Term UI
T751302
Date
05/15/2009
LexicalTag
EPO
ThesaurusID
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