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alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid MeSH Descriptor Data 2023


MeSH Heading
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Tree Number(s)
D03.383.129.385.025
Unique ID
D018350
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018350
Scope Note
An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Entry Term(s)
AMPA
AMPA, (+-)-Isomer
AMPA, (R)-Isomer
AMPA, (R)-Isomer, Monohydrobromide
AMPA, (S)-Isomer
AMPA, (S)-Isomer, Monohydrobromide
Pharm Action
Excitatory Amino Acid Agonists
Registry Number
77521-29-0
Related Numbers
74341-63-2
83643-88-3
83654-13-1
84799-50-8
84799-52-0
CAS Type 1 Name
4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-
Previous Indexing
Ibotenic Acid/analogs & derivatives (1980-1993)
See Also
Receptors, AMPA
Public MeSH Note
94; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID was indexed under IBOTENIC ACID/analogs & derivatives 1980-93
Online Note
use ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (NM) to search ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID 1980-93
History Note
94; was ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (NM) 1980-93
Date Established
1994/01/01
Date of Entry
1993/06/18
Revision Date
2016/05/27
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Preferred
AMPA, (R)-Isomer Narrower
AMPA, (S)-Isomer Narrower
AMPA, (S)-Isomer, Monohydrobromide Narrower
AMPA, (+-)-Isomer Narrower
AMPA, (R)-Isomer, Monohydrobromide Narrower
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