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Cross-Over Studies MeSH Descriptor Data 2026


MeSH Heading
Cross-Over Studies
Tree Number(s)
E05.318.370.150
N05.715.360.325.150
N06.850.520.445.150
Unique ID
D018592
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018592
Annotation
IM general only; when pertinent add CLINICAL TRIAL (PT) or RANDOMIZED CONTROLLED TRIAL (PT)
Scope Note
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Entry Term(s)
Cross-Over Design
Cross-Over Trials
Crossover Design
Crossover Studies
Crossover Trials
Public MeSH Note
95
History Note
95
Date Introduced
1995/01/01
Last Updated
2018/06/29

No Qualifiers
Cross-Over Studies Preferred
Cross-Over Design Related
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