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Clavulanic Acid MeSH Descriptor Data 2022


MeSH Heading
Clavulanic Acid
Tree Number(s)
D02.065.589.099.374.160
D03.633.100.300.374.160
Unique ID
D019818
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019818
Scope Note
A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
Entry Term(s)
BRL-14151
Clavulanate
Clavulanate Potassium
Clavulanic Acid, Monopotassium Salt
Clavulanic Acid, Monosodium Salt
MM-14151
Potassium Clavulanate
Sodium Clavulanate
Pharm Action
beta-Lactamase Inhibitors
Registry Number
23521W1S24
Related Numbers
57943-81-4
58001-44-8
61177-45-5
85A8F32FMG
Q42OMW3AT8
CAS Type 1 Name
4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha))
Previous Indexing
Clavulanic Acids (1978-1997)
Lactams (1976-1982)
Public MeSH Note
98; CLAVULANIC ACID was indexed under CLAVULANIC ACIDS 1978-97 & LACTAMS 1976-82
History Note
98; use CLAVULANIC ACID (NM) 1980-97
Entry Combination
analogs & derivatives:Clavulanic Acids
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2018/06/29
Clavulanic Acid Preferred
MM-14151 Narrower
Clavulanate Potassium Narrower
Clavulanic Acid, Monosodium Salt Narrower
BRL-14151 Narrower
Clavulanate Narrower
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