Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Paraneoplastic Cerebellar Degeneration MeSH Descriptor Data 2026


MeSH Heading
Paraneoplastic Cerebellar Degeneration
Tree Number(s)
C04.588.614.550.650
C04.730.856.650
C10.228.140.252.620
C10.574.781.700
Unique ID
D020362
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020362
Annotation
coord with precoord organ/neopl term + histol type
Scope Note
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Entry Version
PARANEOPL CEREBELLAR DEGENERATION
Entry Term(s)
Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Cerebellar Degeneration, Paraneoplastic
Cerebellar Syndrome, Paraneoplastic
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
Paraneoplastic Cerebellar Syndrome
Previous Indexing
Cerebellar Ataxia (1975-1999)
Paraneoplastic Syndromes (1980-1999)
Public MeSH Note
2000
History Note
2000
Date Introduced
2000/01/01
Last Updated
2009/07/06
Paraneoplastic Cerebellar Degeneration Preferred
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated Narrower
page delivered in 0.138s