NLM Logo

Poloxamer MeSH Descriptor Data 2023


MeSH Heading
Poloxamer
Tree Number(s)
D02.033.455.250.700.682
D05.750.741.667
D25.720.741.667
J01.637.051.720.741.667
Unique ID
D020442
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020442
Scope Note
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Entry Term(s)
Pluronic
Pluronic F-108
Pluronic F-127
Pluronic F-68
Pluronic F68
Pluronic L-101
Pluronic L-121
Pluronic L-81
Pluronics
Poloxalkol
Poloxamer 188
Poloxamer 213
Poloxamer 2930
Poloxamer 338
Poloxamer 407
Poloxamers
Pharm Action
Excipients
Surface-Active Agents
Registry Number
106392-12-5
CAS Type 1 Name
alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer
Previous Indexing
Poloxalene (1976-1998)
Public MeSH Note
99; for POLOXAMERS see POLOXALENE 1974-98
History Note
99; for POLOXAMERS use POLOXALENE 1974-98
Date Established
1999/01/01
Date of Entry
1998/06/10
Revision Date
2020/05/27
Poloxamer Preferred
Poloxamer 188 Narrower
Poloxamer 338 Narrower
Poloxamer 407 Narrower
Poloxamers Broader
Pluronic F-108 Narrower
Pluronic F-127 Narrower
Pluronic F68 Narrower
Pluronic L-101 Narrower
Pluronic L-121 Narrower
Pluronic L-81 Narrower
Pluronics Narrower
Poloxalkol Narrower
Poloxamer 213 Narrower
Poloxamer 2930 Narrower
page delivered in 0.166s