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Selective Estrogen Receptor Modulators MeSH Descriptor Data 2021


MeSH Heading
Selective Estrogen Receptor Modulators
Tree Number(s)
D06.347.360.827
D27.505.696.399.450.360.827
Unique ID
D020845
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020845
Annotation
do not confuse with ESTROGEN RECEPTOR MODULATORS
Scope Note
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
Entry Version
SELECTIVE ESTROGEN RECEPT MODULATORS
Entry Term(s)
Estrogen Receptor Modulator, Selective
Estrogen Receptor Modulators, Selective
SERM
SERMs
Selective Estrogen Receptor Modulator
Registry Number
0
Previous Indexing
Receptors, Estrogen (1996-1999)
See Also
Bone Density Conservation Agents
Public MeSH Note
2000
History Note
2000
Date Established
2000/01/01
Date of Entry
1999/11/08
Revision Date
2013/07/09
Selective Estrogen Receptor Modulators Preferred
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