MeSH Browser

MeSH Heading: Collagen Type IV
Tree Number(s): D12.776.860.300.250.400.100
Unique ID: D024141
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D024141
Annotation: precursors: coord IM with PROCOLLAGEN (IM)
Scope Note: A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Entry Term(s): 7S Collagen; Collagen Type IV, alpha1 Chain; Collagen Type IV, alpha1 Subunit; Collagen Type IV, alpha2 Chain; Collagen Type IV, alpha2 Subunit; Collagen alpha1(IV); Procollagen Type IV; Type IV (Basement Membrane) Collagen; Type IV Collagen; Type IV Procollagen; alpha1(IV) collagen
Previous Indexing: Collagen (1978-2001)
See Also: Porencephaly
Public MeSH Note: 2002; see COLLAGEN 1990-2001; for PROCOLLAGEN TYPE IV see PROCOLLAGEN 1982-2001; for 7S COLLAGEN see COLLAGEN 1982-2001
History Note: 2002; use COLLAGEN 1990-2001; for PROCOLLAGEN TYPE IV use PROCOLLAGEN 1982-2001; for 7S COLLAGEN use COLLAGEN 1982-2001
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2014/06/13

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0004779
Scope Note: A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Terms: Collagen Type IV Preferred Term
Term UI T008997
Date11/28/1988
LexicalTag NON
ThesaurusID NLM (1988); Type IV (Basement Membrane) Collagen
Term UI T008998
Date08/04/1980
LexicalTag NON
ThesaurusID UNK (19XX); Type IV Collagen
Term UI T008996
Date04/20/1989
LexicalTag NON
ThesaurusID NLM (1990)

Concept UI: M0369423
Terms: Collagen Type IV, alpha1 Subunit Preferred Term
Term UI T423911
Date09/13/2000
LexicalTag NON
ThesaurusID NLM (2002); alpha1(IV) collagen
Term UI T466936
Date10/19/2001
LexicalTag NON
ThesaurusID NLM (2003); Collagen alpha1(IV)
Term UI T423915
Date09/13/2000
LexicalTag NON
ThesaurusID NLM (2002); Collagen Type IV, alpha1 Chain
Term UI T423912
Date09/13/2000
LexicalTag NON
ThesaurusID NLM (2002)

Collagen Type IV MeSH Descriptor Data 2025